TRAF3 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES3635
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cytoplasm . Endosome . Mitochondrion . Undergoes endocytosis together with TLR4 upon LPS signaling (By similarity). Co-localized to mitochondria with TRIM35 (PubMed:32562145). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
7187
Human swiss prot no
Q13114
Immunogen
The antiserum was produced against synthesized peptide derived from human TRAF3. AA range:240-289
Isotype
IgG
Observed band
64kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
TNF receptor associated factor 3(TRAF3) Homo sapiens The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010],
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Product Citations
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More Info
More Info
TRAF3 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
