TRAIL rabbit pAb
Vendor: ELK Biotechnology
SKU: ES4241
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
Shipping calculated at checkout.
Documents
Available in stock (100)
Request a Quote
✅ Thank you! Your quote request was sent successfully.
❌ Something went wrong. Please check your details and try again.
- Customs clearance fees may apply
- Worldwide shipping available.
Couldn't load pickup availability
For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cell membrane ; Single-pass type II membrane protein . Secreted . Exists both as membrane-bound and soluble form. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
8743
Human swiss prot no
P50591
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human TNFSF10. AA range:31-80
Isotype
IgG
Observed band
33kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provi
Documents
Documents
Documents
Product Citations
Product Citations
More Info
More Info
TRAIL rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
