Trofinetide

Vendor: Abmole

Type: Proteins

SKU: M45379

$293.25 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Trofinetide, a water-soluble analog of glycine-proline-glutamic acid (GPE), uses the unnatural amino acid 2-methylproline in place of the proline found in the natural compound, and works by enhancing synaptic activity, restoring synaptic structure, inhibiting the effects of inflammatory compounds in the brain, increasing antioxidant responses, reducing injury-induced cell death, and increasing central IGF-1 presence. It has neuroprotective activity and can be used in studies related to Rett syndrome.
Casnumber
853400-76-7
Formula
C13H21N3O6
Mw
315.32
Psmiles
CC1(CCCN1C(=O)CN)C(=O)NC(CCC(=O)O)C(=O)O
Purity
>99.0%
Solubility
Water >100 mg/mL; DMSO 25 mg/mL
Target synonyms
NNZ-2566
Trofinetide

Trofinetide

$293.25 USD