TRY2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES12540
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC;IF;WB
Cellular localization
Secreted, extracellular space.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
5645
Human swiss prot no
P07478
Immunogen
Synthesized peptide derived from human TRY2
Isotype
IgG
Observed band
27kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
IHC-p 1:50-200, WB 1:500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015],
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More Info
More Info
TRY2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
