TTN rabbit pAb
Vendor: ELK Biotechnology
SKU: ES8758
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC;IF;ELISA
Cellular localization
Cytoplasm . Nucleus .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
7273
Human swiss prot no
Q8WZ42
Immunogen
Synthetic peptide from human protein at AA range: 161-210
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
IHC-p 1:50-200, ELISA 1:10000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes.
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Product Citations
Product Citations
More Info
More Info
TTN rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
