TVB-3166

Vendor: Abmole

Type: Molecular

SKU: M8622

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$195.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
TVB-3166

TVB-3166

$195.50 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
TVB-3166 is a cell-permeable pyrrazole derivative that inhibits cellular palmitate synthesis (IC50 <100 nM) by fatty acid synthase (FASN) keto-reductase activity in a potent and reversible manner (IC50 = 42 nM), effectively inhibiting palmitate-dependent survival of various cancer cells in cultures and xenografted tumor growth in mice vivo (60-100 mg/kg/d p.
Casnumber
1533438-83-3
Formula
C24H24N4O
Mw
384.47
Psmiles
CC1=C(C)C(=N[NH]1)C2=C(C)C=C(C)C(=C2)C(=O)N3CC(C3)C4=CC=C(C=C4)C#N
Purity
99.50%
Solubility
DMSO 60 mg/mL
Target synonyms
TVB3166
Technical documents

Documents

Coa

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