UC2288

Vendor: Abmole

Type: Molecular

SKU: M11331

$166.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
UC2288 is a novel p21 attenuator with cellular permeability and oral activity (relatively selective activity for P21), based on the structural synthesis of sorafenib. UC2288 down-regulated the expression of P21 mRNA and reduced the level of P21 protein independently of p53, and had little effect on the stability of P21 protein. UC2288 did not inhibit VEGFR2 and Raf kinases, even at 10 μM.
Casnumber
1394011-91-6
Formula
C20H18ClF6N3O2
Mw
481.82
Psmiles
FC(F)(F)C1=CC=C(OC2CCC(CC2)NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)N=C1
Purity
>99%
Solubility
DMSO 48 mg/mL
UC2288

UC2288

$166.75 USD