UD11 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES12436
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Endoplasmic reticulum membrane ; Single-pass membrane protein . Cytoplasm, perinuclear region .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
54658
Human swiss prot no
P22309
Immunogen
Synthesized peptide derived from human UD11 AA range: 36-86
Isotype
IgG
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Recommended dilutions
WB 1：500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq, Jul 2008],
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More Info
More Info
UD11 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
