uPA rabbit pAb
Vendor: ELK Biotechnology
SKU: ES6602
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC;IF;ELISA
Cellular localization
Secreted .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
5328
Human swiss prot no
P00749
Immunogen
The antiserum was produced against synthesized peptide derived from human uPA. AA range:190-239
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],
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More Info
More Info
uPA rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
