Upadacitinib

Vendor: Abmole

Type: Molecular

SKU: M6297

$161.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research.
Casnumber
1310726-60-3
Formula
C17H19F3N6O
Mw
380.37
Psmiles
CCC1CN(CC1C2=CN=C3C=NC4=C(C=C[NH]4)[N]23)C(=O)NCC(F)(F)F
Purity
99.60%
Solubility
DMSO 75 mg/mL
Target synonyms
ABT-494
Upadacitinib

Upadacitinib

$161.00 USD