Vemurafenib (PLX4032)

Vendor: Abmole

Type: Molecular

SKU: M1761

$63.25 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Vemurafenib (PLX4032) is a first-in-class, potent, selective inhibitor of B-Raf that inhibits RAFV600E and C-RAF-1 activity with IC50s of 31 nM and 48 nM, respectively.In addition, Vemurafenib induces autophagy.
Casnumber
918504-65-1
Formula
C23H18ClF2N3O3S
Mw
489.92
Psmiles
CCC[S](=O)(=O)NC1=CC=C(F)C(=C1F)C(=O)C2=C[NH]C3=NC=C(C=C23)C4=CC=C(Cl)C=C4
Purity
>99.5%
Solubility
DMSO 60 mg/mL
Target synonyms
RG7204; RO5185426
Vemurafenib (PLX4032)

Vemurafenib (PLX4032)

$63.25 USD