Voxelotor

Vendor: Abmole

Type: Molecular

SKU: M9778

$494.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Voxelotor (GBT 440) is a first-in-class, potent polymeric inhibitor of sickle hemoglobin (HbS). Voxelotor (GBT440) binds to the N-terminal a chain of haemoglobin (Hb), increases haemoglobin S (HbS) affinity for oxygen, delays in vitro HbS polymerization and prevents sickling of red blood cells (RBCs).
Casnumber
1446321-46-5
Formula
C19H19N3O3
Mw
337.37
Psmiles
CC(C)[N]1N=CC=C1C2=NC=CC=C2COC3=CC=CC(=C3C=O)O
Purity
>99%
Solubility
DMSO ≥ 90 mg/mL
Target synonyms
GBT440
Voxelotor

Voxelotor

$494.50 USD