VU661013

Vendor: Abmole

Type: Molecular

SKU: M21643

$4,462.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
VU661013 is a novel, potent, selective MCL1 inhibitor with Ki of 97 ± 30 pM to human MCL-1 in a TR-FRET assay. VU661013 destabilizes BIM/MCL1 association, leads to apoptosis in AML, and is active in venetoclax-resistant cells and xenografts.
Casnumber
2131184-57-9
Formula
C39H39Cl2N5O4
Mw
712.66
Psmiles
CC1CN(C(=O)C2=C(CCCOC3=CC(=C(Cl)C(=C3)C)C)C4=CC=C(Cl)C(=C4[N]12)C5=C(C)[N](C)N=C5C)C6=C[N](C)C7=CC=C(C=C67)C(O)=O
Purity
>98.5%
Solubility
DMSO ≥ 90 mg/mL
Target synonyms
VU0661013
VU661013

VU661013

$4,462.00 USD