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VVD-214

VVD-214

Regular price $345.00 USD
Sale price Regular price

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
VVD-214 (RO7589831) is a synthetic lethal allosteric inhibitor of WRN helicase. VVD-214 covalently binds to cysteine 727 of WRN and inhibits ATP hydrolysis and helicase activity.
Casnumber
3026500-20-6
Formula
C20H21F2N3O4S
Mw
437.46
Psmiles
CC(C1=NC=C(C(=N1)OC2=CC=CC=C2)C(=O)NC(C=CS(=O)(=O)C)C3CC3)(F)F
Purity
>99.0%
Solubility
DMSO 90 mg/mL
Target synonyms
RO7589831; VVD-133214
Technical documents

Documents

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