WRG-28

Vendor: Abmole

Type: Molecular

SKU: M29014

$195.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
WRG-28 is a selective, extracellularly acting DDR2 allosteric inhibitor, with an IC50 of 230 nM. WRG-28 inhibits tumor invasion, migration and tumor-supporting effects of cancer-associated fibroblasts (CAFs). WRG-28 inhibits metastatic breast tumor cell colonization in the lungs. WRG-28 also shows good activity of relieving rheumatoid arthritis in CAIA model of mice.
Casnumber
1913291-02-7
Formula
C21H18N2O5S
Mw
410.44
Psmiles
CCNS(=O)(=O)C1=CC=C(C=C1)COC2=CC3=C(C=C2)N=C4C=CC(=O)C=C4O3
Purity
≥99.0%
Solubility
DMSO 15.62 mg/mL (ultrasonic)
WRG-28

WRG-28

$195.50 USD