WZ3146

Vendor: Abmole

Type: Molecular

SKU: M5346

$253.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).
Casnumber
1214265-56-1
Formula
C24H25ClN6O2
Mw
464.95
Psmiles
CN1CCN(CC1)C2=CC=C(NC3=NC=C(Cl)C(=N3)OC4=CC(=CC=C4)NC(=O)C=C)C=C2
Purity
>99.0%
Solubility
93 mg/mL in DMSO
WZ3146

WZ3146

$253.00 USD