YK 3-237

Vendor: Abmole

Type: Molecular

SKU: M7500

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$126.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
YK 3-237

YK 3-237

$126.50 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
YK 3-237 is a boronic acid chalcone analog of combretastatin a4 (CA-4) and a SIRT1 activator that targets mutant p53. YK 3-237 can reduce the acetylation of mutant p53 protein by activating the SIRT1 enzyme, resulting in a significant decrease in the level of mutant p53 protein. YK-3-237 showed antiproliferative activity against tumor cells containing mutant p53 protein.
Casnumber
1215281-19-8
Formula
C19H21BO7
Mw
372.18
Psmiles
COC1=C(OC)C(=CC(=C1)C(=O)/C=C/C2=CC=C(OC)C(=C2)B(O)O)OC
Purity
>99%
Solubility
DMSO 37.22 mg/mL
Technical documents

Documents

Coa

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