Zidesamtinib

Vendor: Abmole

Type: Molecular

SKU: M43803

$862.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Zidesamtinib is a potent, selective, orally active and blood-brain barrier permeable inhibitor of multiple ROS1 fusion and resistance mutations, with IC50 values of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and does not inhibit TRK.May be useful in studies related to non-small cell lung cancer and other solid tumors.
Casnumber
2739829-00-4
Formula
C22H22FN7O
Mw
419.45
Psmiles
CC[N]1N=CC2=C1C3=CC(=C(N)N=C3)OC(C)C4=CC(=CC=C4C5=N[N](C)N=C5C2)F
Purity
>99.0%
Target synonyms
NVL-520
Zidesamtinib

Zidesamtinib

$862.50 USD